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Electrospinning and Photocrosslinking of Highly Modified Fungal Chitosan

Christ HA, Menzel H. Electrospinning and photocrosslinking of highly modified fungal chitosan. Macromol Mater Eng. 2023;308:2200430. doi: 10.1002/mame.202200430.

This study focuses on optimizing the electrospinning process for arylazide-functionalized fungal chitosan. Key parameters such as molecular weight, concentration, and the ratio of chitosan to poly(ethylene oxide) were systematically varied to understand their impact on solution viscosity and fiber morphology. Findings revealed that higher viscosities led to stable jets and aligned microfibers, while lower viscosities resulted in defects. Additionally, a photocrosslinking method was developed to enhance the stability of the nanofiber meshes in aqueous environments. These advancements suggest potential applications in biomedicine and environmental engineering.

Keywords: Fungal chitosan, electrospinning, photocrosslinking, nanofibers, arylazide functionalization