Neyrinck AM, Rodriguez J, Le Roy T, Pachikian BD, Cani PD, Bindels LB, Delzenne NM. Breath volatile metabolome reveals the impact of dietary fibres on the gut microbiota: Proof of concept in healthy volunteers. eBioMedicine. 2022;80:104051. doi: 10.1016/j.ebiom.2022.104051.
This study explores how dietary fibers, specifically chitin-glucan (4.5 g/day), influence gut microbiota and metabolism. Breath analysis in healthy volunteers revealed shifts in volatile compounds, linked to butyrate-producing bacteria like Faecalibacterium. Chitin-glucan modulated breath profiles without affecting digestive comfort, positioning breath analysis as a non-invasive tool to assess dietary fiber effects on gut health.
Keywords: Chitin-glucan, gut microbiota, dietary fibers, prebiotics, breath analysis, butyrate, Faecalibacterium